HBX 41108
CAS No. 924296-39-9
HBX 41108 ( HBX-41108 )
Catalog No. M27424 CAS No. 924296-39-9
HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 61 | Get Quote |
|
5MG | 102 | Get Quote |
|
10MG | 170 | Get Quote |
|
25MG | 402 | Get Quote |
|
50MG | 593 | Get Quote |
|
100MG | 845 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameHBX 41108
-
NoteResearch use only, not for human use.
-
Brief DescriptionHBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
-
DescriptionHBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
-
SynonymsHBX-41108
-
PathwayProteasome/Ubiquitin
-
TargetDUB
-
RecptorBax;Bcl-2;Caspase-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number924296-39-9
-
Formula Weight266.6
-
Molecular FormulaC13H3ClN4O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESClc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zhou D, et al. Antiproliferative steroidal glycosides from rhizomes of Polygonatum sibiricum. Phytochemistry. 2019;164:172-183.
molnova catalog
related products
-
EOAI3402143
EOAI3402143 (Deubiquitinase inhibitor G9, EOAI 3402143) is a novel covalent deubiquitinase Usp9x/Usp24 inhibitor.
-
GNE-6776
GNE-6776 is a novel potent, specific, non-covalent, orally bioavailable USP7 inhibitor with IC50 of 1.34 uM.
-
P-50429
P-50429 (P50429, P 50429) is a potent, selective, covalent deubiquitinase USP7 (EC50=0.42 uM)/USP47 (EC50=1.0 uM) inhibitor.